GHK-Cu Peptide Research: Copper Binding, Mechanisms and Evidence
Updated August 2026. GHK-Cu is the copper(II) complex of the naturally occurring tripeptide glycyl-L-histidyl-L-lysine (GHK). Although it is often described simply as a “copper peptide,” the research literature is more specific: GHK has a strong affinity for Cu(II), forms a defined coordination complex, and has been studied in relation to extracellular-matrix remodeling, fibroblast activity, collagen…


